Adaptive Response Induced by Pre-Exposure to 915 MHz Radiofrequency: A Possible Role for Antioxidant Enzyme Activity

نویسندگان

  • F Zal
  • M A Mosleh-Shirazi
  • M Daneshmand
  • R Zare
  • Z Mostafavi-Pour
چکیده مقاله:

Background: Over the past few years, the rapid use of high frequency electromagnetic fields like mobile phones has raised global concerns about the negative health effects of its use. Adaptive response is the ability of a cell or tissue to better resist stress damage by prior exposure to a lesser amount of stress. This study aimed to assess whether radiofrequency radiation can induce adaptive response by changing the antioxidant balance.Materials and Methods: In order to assess RF-induced adaptive response in tissues, we evaluated the level of GSH and the activity of GR in liver. 50 rats were divided into 5 groups. Three groups were pre-exposed to 915 MHz RF radiation, 4 hours per day for one week at different powers, as low, medium and high. 24 hours after the last exposure to radiation, they were exposed to 4 Gy sublethal dose of gamma radiation and then sacrificed after 5 hours. Their livers were removed, washed and were kept at -80o C until used.Results: Our finding showed that pre-exposure to 915 MHz radiofrequency radiation with specific power could induce adaptive response in liver by inducing changes in the activity and level of antioxidant enzymes.Conclusion: It can be concluded that pre-exposure to microwave radiation could increase the level of GSH and the activity of GR enzyme, although these increases were seen just in low power group, and the GR activity was indicated in medium power group. This increase protects tissue from oxidative damage induced by sublethal dose of gamma radiation.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

adaptive response induced by pre-exposure to 915 mhz radiofrequency: a possible role for antioxidant enzyme activity

background: over the past few years, the rapid use of high frequency electromagnetic fields like mobile phones has raised global concerns about the negative health effects of its use. adaptive response is the ability of a cell or tissue to better resist stress damage by prior exposure to a lesser amount of stress. this study aimed to assess whether radiofrequency radiation can induce adaptive r...

متن کامل

Adaptive Response Induced by Pre-Exposure to 915 MHz Radiofrequency: A Possible Role for Antioxidant Enzyme Activity

BACKGROUND Over the past few years, the rapid use of high frequency electromagnetic fields like mobile phones has raised global concerns about the negative health effects of its use. Adaptive response is the ability of a cell or tissue to better resist stress damage by prior exposure to a lesser amount of stress. This study aimed to assess whether radiofrequency radiation can induce adaptive re...

متن کامل

Micronucleus induction by 915 MHz Radiofrequency Radiation in Vicia faba root tips

The mutagenic effect of radiofrequency electromagnetic field (RF-EMF) is evaluated by the micronucleus (MN) test in secondary roots of Vicia faba seedlings. Root exposures were carried out with 915 MHz continuous wave (CW) radiation for 72h, at power densities of 25, 38, 50 W/m 2 . The specific absorption rate (SAR) corresponding to the experimental exposures was measured with a calorimetric me...

متن کامل

Evaluation of the Validity of a Nonlinear J-Shaped Dose-Response Relationship in Cancers Induced by Exposure to Radiofrequency Electromagnetic Fields

The radiofrequency electromagnetic fields (RF-EMFs) produced by widely used mobile phones are classified as possibly carcinogenic to humans by International Agency for Research on Cancer (IARC). Current data on the relationship between exposure to RF-EMFs generated by commercial mobile phones and brain cancer are controversial. Our studies show that this controversy may be caused by several par...

متن کامل

Adaptive Response in Mice Exposed to 900 MHz Radiofrequency Fields: Primary DNA Damage

The phenomenon of adaptive response (AR) in animal and human cells exposed to ionizing radiation is well documented in scientific literature. We have examined whether such AR could be induced in mice exposed to non-ionizing radiofrequency fields (RF) used for wireless communications. Mice were pre-exposed to 900 MHz RF at 120 µW/cm(2) power density for 4 hours/day for 1, 3, 5, 7 and 14 days and...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


عنوان ژورنال

دوره 7  شماره 2

صفحات  -

تاریخ انتشار 2017-06-01

با دنبال کردن یک ژورنال هنگامی که شماره جدید این ژورنال منتشر می شود به شما از طریق ایمیل اطلاع داده می شود.

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023